Anthelmintic efficacy of medicinal herbs in goats infected with nematode parasites

TitleAnthelmintic efficacy of medicinal herbs in goats infected with nematode parasites
Publication TypeWeb Article
Year of Publication2012
AuthorsZhong, RZ, Wang, Z, Zhou, D, Goetsch, AL, Hart, S, Sahlu, T
Series TitleJournal of Animal Science
Edition90
Type of Medium(E-Supplement 3)
Abstract

Thirty high-percentage Boer does (2.9 ± 0.12 yr; 48 ± 1.9 kg BW) naturally infected with Haemonchus contortus from grazing pasture of Langston University were allocated to 5 groups and moved to a barn to investigate anthelmintic efficacy of three medicinal herbs, Rheum palmatum L. (rhubarb; R), Meliae cortex (melia bark; M), and Quisqualis indica L. (rangoon creeper; Q). Does were given ad libitum access to grass hay and water, along with 200 g/d per doe of a concentrate-based pelleted supplement. Treatments were control (C), R, M, Q, and a 1:1:1 mixture of the three herbs (RMQ). The herbs in powder form were mixed with water at 20 g/100 mL just before drenching. After being acclimated for 7 d, does were drenched with 100 mL of water alone or with the respective herbs at 20 g/d for 10 d. Fecal samples were collected on d 0, 3, 6, 9, 13, and 16 after the start of drenching for worm egg count (FEC). Blood samples were taken on d 0 and 13 for measuring packed cell volume (PCV). Initial FEC was 2,208, 3,933, 3,025, 2,350, and 3,033/g for C, R, M, Q, and RMQ, respectively (SEM = 425.2; P > 0.05). After 10 d of treatment, none of the herbs showed anthelmintic effects. The FEC on d 16 was 1,350, 3,058, 1,525, 825, and 2,067/g for C, R, M, Q, and RMQ, respectively (SEM = 332.9, P > 0.05). Change in PCV was 1.8, 20.1, 9.1, 10.7, and 13.3% for C, R, M, Q, and RMQ, respectively (SEM = 1.68). Compared with C, the PCV value increased in does treated with R and RMQ (P